Charcot-Marie-Tooth disease (CMT)
CMT is a genetically heterogeneous group of inherited peripheral neuropathies that are characterized by progressive distal wasting and loss of reflexes in the muscles of the legs. There several types of CMT including CMT1 and CMT2.
SERVICES
Biomarkers
Genetic Biomarkers
Gene mutations on PMP22 (CMT1A, most common), GJB1 (CMTX1), P0 (CMT1B), and MFN2 (CMT2A).
Diagnostic Biomarkers
- CMT Neuropathy Score (CMTNS)
- CMT Examination Score (CMTES) combined with the
- CMT Functional Outcome Measure (CMTFOM).
- MRI assay of the proximal sciatic nerve
Our approach
is a carefully validated, clinically realistic model for early diabetes mellitus screening and managing of the disease.
Our mathematical & computational tools
enable researchers and decision makers to make better informed decisions.
