Amyotrophic Lateral Sclerosis (ALS)

ALS is a rare, fatal, rapidly progressive neurodegenerative disease characterized by loss of upper and lower motor neurons.



Biological Fluid-based Biomarkers (CSF, Blood, Urine)

Genetic mutation-linked proteins, DNA methylation, Neurodegeneration, Inflammation, Muscle Denervation, miRNA, Metabolism 

Electrophysiology Biomarkers

Motor neuron estimation, Neurophysiological index, Axonal excitability, Electrical impedance myography, Transcranial magnetic stimulation.

Imaging Biomarkers

Magnetic Resonance Imaging (MRI), Magnetic Resonance Spectroscopy (MRS), Positron Emission Tomography (PET).

Our approach

is a carefully validated, clinically realistic model for early diabetes mellitus screening and managing of the disease.


Our mathematical & computational tools

enable researchers and decision makers to make better informed decisions.